The action of sphingomyelinase in lipid monolayers as revealed by microscopic image analysis

MARIA LAURA FANANI; STEFFEN HARTEL; BRUNO MAGGIO; LUISINA DE TULLIO; JORGE JARA; FELIPE OLMOS; RAFAEL GUSTAVO OLIVEIRA

Biochim.Biophys Acta

Elsevier

Lugar: Amsterdan; Año: 2010 vol. 1798 p. 1309 - 1309

0006-3002

span style="FONT-FAMILY: Arial; FONT-SIZE: 11pt; mso-ansi-language: EN-US; mso-fareast-font-family: "Times New Roman"; mso-fareast-language: ES; mso-bidi-language: AR-SA" lang="en">In recent years, new evidence in biomembrane research brought about a holistic, supramolecular view on membrane-mediated signal transduction. The consequences of sphingomyelinase (SMase) driven formation of ceramide (Cer) at the membrane interface involves reorganization of the lateral membrane structure of lipids and proteins from the nm to the m