Ceramide N-Acyl Chain Length: A Determinant of Bidimensional Transitions, Condensed Domain Morphology, and Interfacial Thickness

FERNANDO DUPUY; MARÍA LAURA FANANI ; BRUNO MAGGIO

AMER CHEMICAL SOC

Lugar: Washington; Año: 2011 vol. 27 p. 3783 - 3783

font color="#0040ff" size="2" face="AdvOT51c1769e"> ABSTRACT: Several lipids of biological interest are able to form monomolecular surfaces with a rich variety of thickness and lateral topography that can be precisely controlled by defined variations of the film composition. Ceramide is one of the simplest sphingolipids, consisting of a sphingosine base N-linked to a fatty acid, and is a membrane mediator for cell-signaling events. In this work,