Phase coexistence in films composed of DLPC and DPPC: a comparison between different model membrane systems.

A. MANGIAROTTI, B. CARUSO Y N. WILKE

ELSEVIER SCIENCE BV

Lugar: Amsterdam; Año: 2014 vol. 1838 p. 1823 - 1823

!--[if gte mso 9]> For the biophysical study of membranes, a variety of model systems have been used to measure the different parameters and to extract general principles concerning processes that may occur in cellular membranes. However, there are very few reports in which the results obtained with the different models have been compared. In this investigation, we quantitatively compared the phase coexistence in Langmuir monolayers, freestanding bilayers and supported films composed of a lipid mixture of DLPC and DPPC. Two-phase segregation was observed in most of the systems for a wide range of lipid proportions using fluorescence microscopy. The lipid composition o