Searching for line active molecules on biphasic lipid monolayers

A.A.BISCHOF; A. MANGIAROTTI; N. WILKE,

SOFT MATTER

ROYAL SOC CHEMISTRY

Lugar: CAMBRIDGE; Año: 2015 vol. 11 p. 2147 - 2147

1744-683X

n membranes with phase coexistence, line tension appears as an important parameter for the determination of the amount of domains, as well as their size and their shape, thus defining the membrane texture. Different molecules have been proposed as ?linactants? (i.e. molecules that reduce the line tension, thereby modulating the membrane texture). In this work, we explore the efficiency of different molecules as linactants in monolayers with two coexisting phases of different thicknesses. We tested the linactant ability of a molecule with chains of different saturation degrees, another molecule with different chain lengths and a bulky molecule. In this way, we show in the same system the effect of molecules with chains of different rigidities, with an intrinsic thickness mismatch and with a bulky moiety, thereby analyzing different hypotheses of how a molecule may change the line tension in a monolayer system. Both lipids with different hydrocarbon chains did not act as linact