WILKE NATALIA
Congresos y reuniones científicas
Título:
Dexamethasone and dexamethasone phosphate and their effect on DMPC membrane model
Autor/es:
C.I.CAMARA; CROSIO, M; N. WILKE,; L.M. YUDI
Reunión:
Congreso; 7th European Joint Theoretical/Experimental Meeting on Membranes (EJTEMM 2021); 2021
Resumen:
Dexamethasone (Dex) and Dexamethasone phosphate (Dex-P) are synthetics glucocorticoids with a high anti-inflammatory and immunosuppressor action [1]. Both drugs are used in a wide range of diseases from tumor to asthma attack [2?4]. Recently, Dexamethasone has become more renowned because it reduces the mortality in critical patients with SARs-COVID-19 connected to assisted breathing [5,6].We studied the variation of the properties of DMPC monolayers as Dex and Dex-P inserted into the film in different molar proportions. With this aim, we used complementary techniques such as compression isotherms, Brewster angle microscopy (BAM), and insertion experiments. Vesicle shape fluctuations were also analyzed
