Novel antibodies reacting with two neighboring gangliosides are induced in rabbits immunized with bovine brain gangliosides

MOYANO, AL; COMÍN, R; VILCAES, AA; ROTH, GA; IRAZOQUI FJ; NORES, GA

OXFORD UNIV PRESS INC

Lugar: Oxford; Año: 2012 vol. 22 p. 1768 - 1768

font color="#231f20" size="2" face="AdvTT2cba4af3.B"> Immunization of rabbits with bovine brain gangliosides induced an experimental neuropathy, with clinical signs resembling Guillain–Barré syndrome. All the immunized animals developed immunoglobulin G immunoreactivity to GM1 ganglioside. In a few (4 of 27) animals, an additional anti-ganglioside antibody population showing an unusual binding