Memory expression is independent of memory labilization/reconsolidation

KARINA A BARREIRO ; LUIS D SUÁREZ; MARÍA V LYNCH; VÍCTOR A MOLINA AND ALEJANDRO DELORENZI

ACADEMIC PRESS INC ELSEVIER SCIENCE

Lugar: Amsterdam; Año: 2013 vol. 106 p. 283 - 283

font face="AdvGulliv-R" size="1"> There is growing evidence that certain reactivation conditions restrict the onset of both the destabilization phase and the restabilization process or reconsolidation. However, it is not yet clear how changes in memory expression during the retrieval experience can influence the emergence of the labilization/ reconsolidation process. To address this issue, we used the context-signal memory model of Chasmagnathus. In this paradigm a short reminder that does not include reinforcement allows us to evaluate memory labilization and reconsolidation, whereas a short but reinforced reminder restricts the onset of such a process. The current study investigated the effects of the glutamate antagonists, APV (0.6 or 1.5 l