The involvement of the GABAergic system in the formation and expression of the extinction memory in the crab Neohelice granulate

CARBO, M.; MOLINA, V.A. AND M.E. PEDREIRA

WILEY-BLACKWELL PUBLISHING, INC

Lugar: Londres; Año: 2013 vol. 38 p. 3302 - 3302

font size="1" face="AdvPSHEL"> There is growing interest in the neurobiological mechanisms involved in the extinction of aversive memory. This cognitive process usually occurs after repeated or prolonged presentation of a conditioned stimulus that was previously associated with an unconditioned stimulus. If extinction is considered to be a new memory, the role of the c-aminobutyric acid system (GABAergic system) during extinction memory consolidation should be similar to that described for the original trace. It is also accepted that negative modulation of the GABAergic system before testing can impair extinction memory expression. However, it seems possible to speculate that inhibitory mechanisms ma