The influence of stress on fear memory processes.

I.D. MARTIJENA AND V.A. MOLINA.

ASSOC BRAS DIVULG CIENTIFICA

Lugar: San Pablo; Año: 2012 vol. 45 p. 308 - 308

font lang="en" size="1" face="ArialMT"> It is well recognized that stressful experiences promote robust emotional memories, which are well remembered. The amygdaloid complex, principally the basolateral complex (BLA), plays a pivotal role in fear memory and in the modulation of stress-induced emotional responses. A large number of reports have revealed that GABAergic interneurons provide a powerful inhibitory control of the activity of projecting glutamatergic neurons in the BLA. Indeed, a reduced GABAergic control in the BLA is essential for the stress-induced influence on the emergence of associative fear memory and on the generation of long-term potentiation (LTP) in BLA neurons. The extracellular signal-regulated kinase (ERK) subfamily of the mitogen-activated protein kinase (MAPK) signaling pathway i