Memory consolidation and reconsolidation in an invertebrate model: The role of the GABAergic system

CARBÓ TANO, M; MOLINA, VA; MALDONADO, H. AND M.E.PEDREIRA.

Elsevier Science

Año: 2009 vol. 158 p. 387 - 387

b> Consolidation theory assumes that memories are labile during a limited time window after acquisition, but as time passes, memories become stable and resistant to amnesic agents. However, the vision of immutable memories after consolidation has been challenged. Thus, after the presentation of a reminder, the reactivated old memories become labile and again susceptible to amnesic treatments. This process implies a re-stabilization phase, usually referred to as reconsolidation. Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter both in the Central nervous system (CNS) and in the periphery. A considerable amount of evidence has arisen from different s