Reconsolidation of declarative memory in humans

FORCATO C., BURGOS V.L., ARGIBAY P.F., MOLINA V.A., PEDREIRA M.E., MALDONADO H

Cold Spring Harbor Laboratory Press

Año: 2007 vol. 14 p. 295 - 295

font color="#272525" size="1" face="AlbertusMT"> The reconsolidation hypothesis states that a consolidated memory could again become unstable and susceptible to facilitation or impairment for a discrete period of time after a reminder presentation. The phenomenon has been demonstrated in very diverse species and types of memory, including the human procedural memory of a motor skill task but not the human declarative one. Here we provide evidence for both consolidation and reconsolidation in a paired-associate learning (i.e., learning an association between a cue syllable and the respective response syllable). Subjects were given two training sessions with a 24-h interval on distinct verbal material, and afterward, they received at testing two successive retrievals corresponding to the first and second learning, respectively. Two main