Normally occurring human anti-GM1 antibodies are part of the immune response to bacteria

ALANIZ ME; LARDONE RD; YUDOWSKY SL; FARACE MI; NORES GA

INFECTION AND IMMUNITY

Año: 2004 vol. 73 p. 2148 - 2148

0019-9567

p class="Textodenotaalfinal" style="MARGIN: 0cm 0cm 0pt; LINE-HEIGHT: 200%; mso-pagination: widow-orphan; mso-hyphenate: none; tab-stops: 36.0pt 72.0pt">Anti-GM1 antibodies of the IgM isotype are normal components of the antibody repertoire of adult human sera. Using a sensitive HPTLC immunostaining assay we found that these antibodies are absent in umbilical vein and days old children, but they start to be detected after one month of life. Although most of the children older than six months of age are positive, there are still some few negative children.  The apparition of anti-GM1 IgM-antibodies show