A new type of anti-ganglioside antibodies present in neurological patients

LOPEZ PABLO H. H.; COMÍN ROMINA; VILLA ANDRES M.; DI EGIDIO MARIANA; ZAISAR ROBERTO D.; SICA ROBERTO E. P.; NORES GUSTAVO A.

BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE

Año: 2006 vol. 1762 p. 357 - 357

0925-4439

p class="MsoNormal" style="MARGIN: 0cm 0cm 0pt; LINE-HEIGHT: 200%; TEXT-ALIGN: justify; tab-stops: 36.0pt 72.0pt">High titers of anti-GA1 antibodies have been associated with neurological syndromes. In most cases, these antibodies cross-react with the structurally related glycolipids GM1 and GD1b, although specific anti-GA1 antibodies have also been reported. The role of specific anti-GA1 antibodies is uncertain since the presence of GA1 in the human nervous system has not been clarified.