Shedding light on the regulation of the metabolism of phospholipids

BEATRIZ LEONOR CAPUTTO; MARIO E GUIDO

ELSEVIER SCIENCE BV

Lugar: Amsterdam; Año: 2002 vol. 1583 p. 1 - 1

font face="AdvTT5843c571" size="2"> All cells contain an enormous variety of phospholipids as major components of their membranes. The ability of phospholipids to assume the bilayer organization characteristic of membranes is determined by their amphipathic nature that results from the presence in these molecules of a hydrophilic head group and a hydrophobic region. Although the chemical nature of the different phospholipids can vary substantially, the final macromolecular organization they assume in water has similar characteristics. In this organization, the polar region tends to orientate towards the aqueous phase and the hydrophobic regions, sequestered away from water, interact with each other, creati