Rhythms of glycerophospholipid synthesis in retinal inner nuclear layer cells.

GARBARINO-PICO E,; VALDEZ DJ,; CONTIN MA,; PASQUARE SJ,; CASTAGNET PI,; GIUSTO NM,; BEATRIZ LEONOR CAPUTTO; GUIDO ME,

PERGAMON-ELSEVIER SCIENCE LTD

Lugar: Amsterdam; Año: 2005 vol. 47 p. 260 - 260

p class="MsoNormal" style="MARGIN: 0pt; mso-layout-grid-align: none">Abstract The present study demonstrates that the biosynthesis of phospholipids in the inner nuclear layer cells of the chicken retina displays daily rhythms under constant illumination conditions. The vertebrate retina contains circadian oscillators and photoreceptors (PRCs) that temporally regulate its own physiology and synchronize the whole organism to the daily environmental changes. We have previously reported that chicken photoreceptors and retinal ganglion cells (RGCs) present significant daily variations in their phospholipid biosynthesis under constant illumination conditions. Herein, we demonstrate that cell preparations highly enriched in inner nuclear layer cells also exhibit a circadian-regulated ph