c-Fos is a surface-pressure dependent diverter of phospholipase activity

GA BORIOLI; ML FANAN; BL CAPUTTO; B MAGGIO

ACADEMIC PRESS INC ELSEVIER SCIENCE

Lugar: Amsterdam; Año: 2002 vol. 295 p. 964 - 964

font face="AdvPSTim-B" size="1"> Abstract c-Fos, a transcription factor, associates to endoplasmic reticulum and modulates phospholipid biosynthesis. Its surface thermodynamic properties allow it to differentially interact with phospholipid monolayers with a selective dependence on the lipid polar head group and the lateral surface pressure. We explored the c-Fos ability to modulate phospholipid degradation by phospholipases (ppPLA2, Bacillus cereus