Perinatal undernutrition affects brain modulatory capacity of beta adrenergic receptors in adult rats.

KELLER, E., CUADRA, G.R., MOLINA, V.A. AND ORSINGHER, O.A.

JOURNAL OF NUTRITION

American Society of Nutritional Sciences

Lugar: United States; Año: 1990 vol. 120 p. 305 - 305

0022-3166

p class="MsoNormal" style="MARGIN: 0cm 0cm 0pt; TEXT-ALIGN: justify; mso-layout-grid-align: none">Rats submitted to a protein deprivation schedule from the perinatal period until 50 d of age (dams and/or rats fed an 8% casein diet) and then fed a commercial nonpurified diet for at least 90 d were assayed to evaluate the up- and down-regulation of Beta-adrenergic receptors in brain structures following prolonged (7 d) treatment with propranolol or desipramine, drugs that induce changes in receptor density. Propranolol produced up-regulation (increased Bmax) in the frontal cortex of both control and deprived animal