Artículos
Título:
Modifications in alpha-MSH concentrations in different hypothalamic areas during the estrous cycle in the rat
Autor/es:
SCIMONELLI TN; CELIS ME
Revista:
Acta Physiol Pharmacol Latinoam
Editorial:
Asociación Latinoamericana de Ciencias
Referencias:
Año: 1986 vol. 36 p. 431 - 431
Resumen:
he present experiments were undertaken to examine the pattern of
alpha-MSH during the estrous cycle in different hypothalamic areas and
assess if during the whole estrous cycle the MSH which arises from
proopiomelanocortin (POMC) has the same concentrations pattern as MSH
from the dorso-lateral hypothalamus. MSH concentration of the mediobasal
hypothalamus (MBH), preoptic area (POA) and dorso-lateral hypothalamus
(DLH) was measured using a specific radioimmunoassay. The rats were
sacrificed every four hours by perfusion. It is possible to observe a
circadian rhythm in all the areas studied except in MBH during estrus.
The MSH concentration in MBH was high during the light period,
inversely, in POA the concentration remained low. In general, when MSH
is high in MBH, it is low in POA and vice versa. The pattern of MSH in
DLH is very similar to that observed for the peptide in POA.