Anxiety-like behavior induced by IL-1beta is modulated by alpha-MSH trough central melanocortin-4 receptors

CRAGNOLINI AB; SCHIÖTH H; SCIMONELLI TN

Elsevier

Año: 2006 p. 1451 - 1451

p style="margin: 0cm 0cm 0pt; line-height: 200%; text-align: justify;" class="MsoNormal">Abstract The proinflammatory cytokine interleukin-1beta (IL-1b) influences neuroendocrine activity and produces other effects, including fever and behavioral changes such as anxiety. The melanocortin neuropeptides, such as alpha-melanocyte-stimulating hormone (a