Chronic Stress-Induced Changes in Locus Coeruleus Neuronal Activity

LUIS A. PAVCOVICH, LILIANA M. CANCELA, MARTA VOLOSIN,

PERGAMON-ELSEVIER SCIENCE LTD

Año: 1990 vol. 24 p. 293 - 293

font face="Times New Roman" size="1"> PAVCOVICH, L. A., L. M. CANCELA, M. VOLOSIN, V. A. MOLINA AND 0. A. RAMIREZ. Chronic stress-induced changes in locus coeruleus neuronal activity. BRAIN RES BULL 24(2) 293-296, 1990.-Locus coeruleus (LC) activity was assessed in rats exposed to either acute or chronic stress. After one immobilization session, the number of spontaneously active LC neurons dramatically decreased. On the other hand, repeated restraint sessions enhanced noradrenergic (NA) transmission and the inhibitory effect of clonidine (CLON)