Effect of Chronic Variable Stress on Monoamine Receptors: Influence of Imipramine Administration

V. A. MOLINA, M. VOLOSIN, L. CANCELA, E. KELLER,

PERGAMON-ELSEVIER SCIENCE LTD

Año: 1990 vol. 35 p. 335 - 335

font face="Times New Roman" size="1"> MOLINA, V. A., M. VOLOSIN, L. CANCELA, E. KELLER, V. S. MUROA AND A. M. BASSO. Effect of chronic variable stress on monoamine receptors: Influence of imipramine administration. PHARMACOL BIOCHEM BEHAV 35(2) 335-340, 1990.--Adult male rats were exposed to a series of unpredictable stressors, a paradigm considered to be a model of experimental depression, with or without concurrent administration of imipramine. One day after the last stress event of the chronic regime, binding of cortical beta-adrenoreceptors and the behavioral serotonin (5-HT) syndrome induced by 5-methoxy-N,N,dimethyhryptamine (5-MeODMT) were determined in all the experimental gr