Behavioral Responses to Ethanol in Rats Perinatally Exposed to Low Lead Levels

MIRIAM B. VIRGOLINI, LILIANA M. CANCELA AND SUSANA FULGINITI

PERGAMON-ELSEVIER SCIENCE LTD

Año: 1999 p. 551 - 551

i> Behavioral responses to ethanol in rats perinatally exposed to low lead levels. NEUROTOXICOL TERATOL 21 (5) 551–557, 1999.—Wistar rats were exposed to 220 ppm of lead (Pb) in the drinking water from conception to the end of the nursing period (postnatal day 25). Maternal blood Pb levels at this time were 25 m g/dl. Male offpring were tested at the age of 35 or 70 days. We studied the anxiolytic response to 0.5–2.0 g/kg ethanol in an elevated plus maze test and preference for increasing ethanol solutions (2%, 4%,