Antidepressants attenuate both the enhanced ethanol intake and ethanol-induced anxiolytic effects in diazepam withdrawn rats

MARTIJENA I.D, BUSTOS S.G, BERTOTTO M.E. AND MOLINA V.A

European Neuropsychopharmacology

ELSEVIER

Año: 2005 vol. 15 p. 119 - 119

0924-977X

p class="MsoNormal" style="MARGIN: 0cm 0cm 0pt">We have recently shown that the abrupt discontinuation of chronic diazepam (DZM) administration facilitated ethanol consumption and enhanced the anxiolytic properties of ethanol. Tricyclic antidepressants such as desipramine and the selective serotonin reuptake inhibitor fluoxetine have been shown to reduce alcohol intake in rodent models of alcoholism and in alcoholics who are