Metyrapone pretreatment prevents the behavioral and neurochemical sequelae induced by stress

CALVO N, MARTIJENA ID, MOLINA VA, VOLOSIN M

ELSEVIER SCIENCE BV

Año: 1998 p. 227 - 227

b> Abstract In the present study, we examined the effect of metyrapone, an inhibitor of corticosterone CS. synthesis, on the behavioral and neurochemical sequelae induced by a brief restraint session. A 15-min stress period induced an anxiogenic-like behavior on the elevated plus-maze