Larrea divaricata Cav. enhances the innate immune

MARTINO RF, DAVICINO RC, MATTAR MA,CASALI YA, CORREA SG, MICLAIZZI B

ACADEMIC JOURNALS

Año: 2011 vol. 5 p. 753 - 753

p style="MARGIN: 0cm 0cm 0pt; mso-layout-grid-align: none" class="MsoNormal">Larrea divaricata Cav. is a plant used in Argentinean folk medicine. The aim of this work was to evaluate the effect of a purified fraction (F1) obtained from an extract of the plant on murine macrophages (MØ) against a systemic infection by Candida albicans. Mice were divided in four groups: 1) healthy without treatment; 2) healthy with F1 treatment; 3) infected, without treatment; and 4) infected with F1 treatment. Peritoneal MØ were harvested and the following tests were performed: Apoptosis, phagocytosis, hydrogen peroxide (H2O2) production, nitric oxide (NO) production, determination of seric TNF- a