Artículos
Título:
Expression and distribution of IGF-1 receptors containig a novel beta subunit variant (betagc) enriched in the growth cone of developing neurons
Autor/es:
F. MASCOTTI; A. CÁCERES; K.H. PFENNINGER; S. QUIROGA
Revista:
The Journal of Neurosciences
Referencias:
Año: 1997 vol. 17 p. 1447 - 1447
Resumen:
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bgc is a b-subunit variant of the insulin-like growth factor-1
(IGF-1) receptor highly enriched in growth cone membranes
prepared by subcellular fractionation of fetal rat brain (Quiroga
et al., 1995). The present study is focused on the expression
and on the cellular and subcellular distribution of bgc in developing
neurons and differentiating PC12 cells. In the developing
cerebral cortex and, at least at early stages, in cultured primary
neurons,