Environmental poliovirus surveillance during oral poliovirus vaccine and inactivated poliovirus vaccine use in Córdoba Province, Argentina.

JUDITH E. MUELLER; MAËL BESSAUD; Q. SUE HUANG; LAURA C. MARTÍNEZ; PATRICIA A. BARRIL; VIVIANE MOREL; JEAN BALANANT,; JUDY BOCACAO; JOANNE HEWITT; BRAD D. GESSNER; FRANCIS DELPEYROUX; SILVIA V. NATES

AMER SOC MICROBIOLOGY

Año: 2009 vol. 75 p. 1395 - 1395

his study compares the presence of environmental poliovirus in two Argentinean populations using oral poliovirus vaccine (OPV) or inactivated poliovirus vaccine (IPV). From January 2003 to December 2005, Córdoba City used IPV in routine infant immunizations, with the exception of intermittent OPV use in August 2005. Between May 2005 and April 2006, we collected weekly wastewater samples in Córdoba City and the province's three major towns, which continued OPV use at all times. Wastewater samples were processed and analyzed for the presence of poliovirus according to WHO guidelines. During the months of IPV use in Córdoba City, the overall proportion of poliovirus-positive samples was 19%. During an intermittent switch from IPV to OPV, this proportion increased to 100% within 2 months. During the 3 months when IPV was reintroduced to replace OPV, a substantial proportion of samples (25%) remained positive for poliovirus. In the OPV-using sites, on average, 54% of samples were polioviru