Título:
Genetic and antigenic evolution profiles of G1 rotaviruses in córdoba, Argentina, during a 27-year period (1980-2006).
Resumen:
enetic and Antigenic Evolution Profiles of G1 Rotaviruses in Co´rdoba, Argentina, During a 27-Year Period (1980?2006) Patricia Barril,1,2* Laura Martı´nez,1 Miguel Giordano,1 Gisela Masachessi,1 Marı´a Isa,1 Jorge Pavan,1 Graciela Glikmann,3 and Silvia Nates1 1Virology Institute ??Dr. J. M. Vanella??, School of Medical Sciences, National University of Co´rdoba, Co´rdoba, Argentina 2National Council of Science and Technology (CONICET), Argentina 3Laboratory of Immunology and Virology, Department of Science and Technology, National University of Quilmes, Buenos Aires, Argentina Rotavirus G1 strains represent the most common genotype that causes diarrhea in humans and has been incorporated into both, monovalent and multivalent, rotavirus licensed vaccines. The aim of this study was to determine the evolution profile of G1 rotaviruses in Co´ rdoba, Argentina, over a 27-year period (1980?2006). Intragenotype diversity, represented by lineages within rotavirus ci