Loss maternally derived measles immunity in Argentinian infants.

NATES SV, GIORDANO MO, MEDEOT SI, MARTÍNEZ LC, BAUDAGNA AM, NARETTO E, GARRIDO P, DE WOLFF CD.

LIPPINCOTT WILLIAMS & WILKINS

Lugar: Philadelphia; Año: 1998 vol. 17 p. 313 - 313

ediatr Infect Dis J. 1998 Apr;17(4):313-6. Loss maternally derived measles immunity in Argentinian infants. Nates SV1, Giordano MO, Medeot SI, Martínez LC, Baudagna AM, Naretto E, Garrido P, De Wolff CD. Author information Abstract BACKGROUND: Measles immunization of children at 1 year of age with a single dose of the current vaccine has successfully reduced measles incidence in Argentina. However, the optimal schedule of measles vaccination of young infants would balance the risk of early loss of maternal antibody in the majority of infants with the risk of primary vaccine failure because of passive measles immunity. This study is the first to document a significant association between loss of passive measles antibody and age among infants born in 1995 and 1996 in Córdoba City, Argentina. METHODS: This is a seroprevalence study of 340 infants to investigate the duration of transplacentally derived measles antibody, assayed by a neutralization test, during the first 8 months