Modified seroneutralization assay for measles virus antibody detection.

NATES SV, REY GY, GIORDANO MO, ZAPATA MT, DEPETRIS A, BOSHELL J.

Research in virology

Amsterdam ; New York : Elsevier, c1989-c1998.

Año: 1994 vol. 145 p. 45 - 45

0923-2516

es Virol. 1994 Jan-Feb;145(1):45-9. Modified seroneutralization assay for measles virus antibody detection. Nates SV1, Rey GY, Giordano MO, Zapata MT, Depetris A, Boshell J. Author information Abstract We describe a simple, inexpensive, sensitive and specific modified seroneutralization assay for use on a wide scale to screen for the presence of measles antibodies. After only one reaction (1 h) and a 3-day incubation period at 37 degrees C, the test can be easily read using a rapid, inexpensive methylene blue/phenol staining procedure. The determination of protective antibody titres by modified and standard seroneutralization methods was strongly correlated (corr. coff. = 0.98)