Artículos
Título:
Immunoglobulin M antibody response to measles virus following natural virus infection, primary vaccination, and reexposure to the virus.
Autor/es:
NATES S, REY G, GIORDANO M, MEDEOT S, DEPETRIS A, BOSHELL J, DE WOLFF CD.
Editorial:
MARY ANN LIEBERT INC
Referencias:
Lugar: New York; Año: 1997 vol. 10 p. 165 - 165
Resumen:
iral Immunol. 1997;10(3):165-73.
Immunoglobulin M antibody response to measles virus following natural virus infection, primary vaccination, and reexposure to the virus.
Nates S1, Rey G, Giordano M, Medeot S, Depetris A, Boshell J, de Wolff CD.
Author information
Abstract
Evaluation of the measles virus ELISA kit (Merck) to detect specific IgM as an indicator of primary measles antibody response was carried out. A modification of the manufacturer's cutoff value interpretation was introduced to allow for equivocal results in addition to positive and negative ones. With this modification, the test assayed gave an overall reproducibility of 96.16%. The IgM seropositivity rate for seroneutralization-confirmed measles cases was 100% for naturally infected measles subjects and 90% for primary measles vaccinated subjects. Individuals with positive neutralizing antimeasles antibodies in close contact with a confirmed measles case gave the following measles IgM ELISA results: 54.54% negat