Equivalencia Farmacéutica en Comprimidos Recubiertos de Diclofenac sódico

MARÍA EUGENIA, OLIVERA; DANIEL ALBERTO, ALLEMANDI; RUBEN HILARIO, MANZO; MARIA EUGENIA OLIVERA

COLEGIO FARMACEUTICOS PROVINCIA DE BUENOS AIRES

Lugar: Buenos Aires; Año: 2003 vol. 22 p. 143 - 143

p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt; mso-layout-grid-align: none; mso-pagination: none; tab-stops: 28.3pt 75.1pt" class="MsoNormal">Pharmaceutical equivalence of sodium diclofenac delayed-release tablets?. Sodium diclofenac 50 mg tablets belonging to 6 different Argentinian manufacturers and named as ?coated tablets?, were selected to test them according to USP dissolution requirements. Sodium diclofenac is codified by USP 25 as delayed-release tablets. The goals were to determine if the test products satisfy USP dissolution requirements and, in consequence, if they may be regarded as similar drug products according to the argentinian regulations. Results showed that only two products complied the requirements for ?delayed-release tablets? and may be regarded as             ?similar drug products?. The rest did not comply USP requi