Resumen:
igh-fat diets (HFDs) are an acknowledged risk factor for male subfertility, but the underlying mechanismsremain unclear. In the present study we compared the effects of two HFDs with different v6 : v3 ratios, one enriched withsoy oil (SOD; v6 :v3 ¼ 9.62) and another enriched with sunflower oil (SFOD; v6 : v3 ¼ 51.55), with those of acommercial diet (CD; v6 : v3 ¼ 19.87), supplied from pregnancy to adulthood, on morphometric parameters andreproductive performance in adult male mice (recommended v6 :v3 for rodents ¼ 1?6). Bodyweight was significantlyhigher in the SFOD than CD group, and relative testicular weight was significantly lower in the SFOD than the other twogroups. SFOD altered sperm performance: it reduced sperm viability (mean s.e.m.; 76.00 1.35% vs 82.50 1.45%and 80.63 1.00% in the SFOD vs CD and SOD groups respectively; P , 0.05) and increased the percentage of immaturespermatozoa (71.88 7.17% vs 51.38 5.87% and 48.00 5.72% in the SFOD vs CD and SOD groups respective