Alphaviruses: Serological Evidence of Human Infection in Paraguay (2012-2013)

FÁTIMA MARÍA CARDOZO*; BRENDA S. KONIGHEIM*; GUILLERMO ALBRIEU-LLINÁS, ; MARÍA ELISA RIVAROLA,; JAVIER AGUILAR, ; ALEJANDRA ROJAS, ; AGUSTÍN QUAGLIA, ; MALVINA PÁEZ; , YVALENA GUILLÉN,; LUIS ADRIAN DÍAZ,; MARÍA ASUNCIÓN VALLEJOS,; LILIAN HEREBIA, ; MARÍA LIDIA RECALDE,; MARTA SILVIA CONTIGIANI,; LAURA PATRICIA MENDOZA

VECTOR-BORNE AND ZOONOTIC DISEASES

MARY ANN LIEBERT INC

Año: 2018 vol. 18 p. 266 - 266

1530-3667

lphaviruses can produce febrile illness and encephalitis in dead-end hosts like horses and humans. Within this genus, the Venezuelan Equine Encephalitis virus (VEEV) complex includes pathogenic epizootic subtypes and enzootic subtypes that are not pathogenic in horses (except subtype IE, Mexican strains), although they can cause febrile symptoms in humans. The Rio Negro virus (RNV - VEEV subtype VI) circulates in Argentina, where it was associated with undifferentiated febrile illness. Mayaro (MAYV) and Una (UNAV) viruses belong to a different group, the Semliki Forest virus complex, with confirmed circulation. The present study aimed to determine RNV, MAYV and UNAV seroprevalences by plaque reduction neutralization test in 652 samples of Paraguayan individuals mainly from the Central Department, between years 2012 and 2013. Samples with antibodies titer >1:20 againstRNV were also tested for Mosso das Pedras (MDPV) - subtype IF, subtype IAB, and Pixuna (PIXV)-subtype IV viruses that b