GODINO AGUSTINA
Artículos
Título:
Characterization of the bacteriocins and the PrtR regulator in a plant-associated Pseudomonas strain
Autor/es:
GODINO, AGUSTINA; FERNANDEZ, MARICRUZ; PRÍNCIPE, ANALÍA; VIVIANA LOPEZ RAMIREZ; JOSÉ MIGUEL QUESADA; VIRGINIA RIGO; MANUEL ESPINOSA-URGEL; GUSTAVO MORALES; FISCHER, SONIA
Revista:
JOURNAL OF BIOTECHNOLOGY
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Lugar: Amsterdam; Año: 2019
ISSN:
0168-1656
Resumen:
he emergence of antibiotic resistant bacterial strains demands the development of new antimicrobial agents. Inthe last decades, bacteriocins have gained significant interest due to their potential application as biopreservativesin the food industry and as therapeutic agents in medicine. Recent studies project the use of theseantimicrobials in agriculture as biocontrol agents. The characterization of bacteriocins and their genetic regulation,however, have been scarcely studied in plant-associated bacteria.In this report, an in-silico and proteomic analysis was performed to identify the bacteriocins produced byPseudomonas fluorescens SF4c. More than one functional bacteriocin was detected in this strain (S-type bacteriocinsand phage-tail-like bacteriocins [tailocins]). It is known that the regulator PrtR represses bacteriocinproduction in P. aeruginosa under normal condition. However, the mechanism for tailocin regulation remainsunknown in plant-associated pseudomonads. In this work, an