Do aging, drinking, and having unhealthy weight have a synergistic impact on semen quality?

RAMÍREZ, NICOLÁS; ESTOFÁN, GUSTAVO; TISSERA, ANDREA; MOLINA, ROSA; LUQUE, EUGENIA MERCEDES; TORRES, PEDRO JAVIER; MANGEAUD, ARNALDO; MARTINI, ANA CAROLINA

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS.

SPRINGER/PLENUM PUBLISHERS

Año: 2021 vol. 38

1058-0468

urpose: To evaluate if age, alcohol consumption, and body mass index (BMI) have synergistic effects on seminal quality, and to rank these factors based on their impact on semen. Methods: Retrospective study of 9464 patients attending an andrology laboratory. Data on patients? age and daily alcohol intake were provided by the patients. BMI was recorded in the laboratory. Seminal parameters evaluated were volume, sperm concentration and total count, motility, morphology, viability, nuclear maturity, and membrane functional integrity. Results: All the seminal parameters evaluated were affected by the synergistic interaction Age x BMI, suggesting that this combination is more potent in affecting semen quality. The variables sperm morphology and nuclear maturity seemed to be especially susceptible since they were affected by the three synergistic interactions. In the logistic regression analysis, age was the most powerful factor since it impacted first on five of the nine parameters, impac