Artículos
Título:
Hepatitis A outbreak affecting men who have sex with men (MSM) in central Argentina, occurred in July 2017–April 2018, later than the European outbreak
Autor/es:
MARIOJOULES, JORGE; CASTRO, GONZALO; PISANO, MARÍA BELÉN; BARBERO, PAULA; FANTILLI, ANABELLA; BORDA, MARIEL; CANNA, FERNANDO; BARBÁS, GABRIELA; RÉ, VIVIANA
Revista:
JOURNAL OF CLINICAL VIROLOGY : THE OFFICIAL PUBLICATION OF THE PAN AMERICAN SOCIETY FOR CLINICAL VIROLOGY.
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Año: 2019 vol. 117 p. 49 - 49
Resumen:
ackground: During June-2016?May-2017, several outbreaks of HA were recorded in Europe, especially described in MSM. In our area since July-2017, an increase of hepatitis A (HA) notification was reported. Objective: In order to understand the unusual increase of cases occurred in the central region of Argentina, the aim of this study was to describe, characterize and contextualize epidemiologically the HA outbreak occurred this area, until April2018. Study design: HA cases (positive anti-HAV IgM) obtained from the calendar week 29/2017 in which the first case of MSM was recognized were included in our study. HAV RNA detection and molecular characterization was performed from serum samples and/or stool by RT - PCR of VP1/2A genomic region (360bp). Results: Of the 32 cases notified, 87.5% of them were unvaccinated men and 69.6% were MSM (mean age 31.9 years). All MSM associated HAV sequences were genotyped as IA, and clustered with the VRD 521?2016 strain, responsible of causing outbreak