PREVALENCE OF SARCOPENIA AND WHOLE-BODY COMPOSITION IN RHEUMATOID ARTHRITIS

MARÍA L BRANCE ; SILVANA DI GREGORIO ; BERNARDO A PONS-ESTEL ; NORBERTO J QUAGLIATO ; MARISA JORFEN ; GUILLERMO BERBOTTO ; NOEL CORTESE ; JUAN C RAGGIO ; MARIANO PALATNIK ; IGNACIO CHAVERO ; JUAN SOLDANO ; ROMULO WONG ; LUIS DEL RIO ; ARIEL SÁNCHEZ ; LUCAS R BRUN

JCR - JOURNAL OF CLINICAL RHEUMATOLOGY

LIPPINCOTT WILLIAMS & WILKINS

Lugar: Philadelphia; Año: 2021 vol. 27 p. 153 - 153

1076-1608

ackground: Rheumatoid arthritis (RA) is a chronic autoimmune disease which leads to joint deformity and disability and also muscle involvement. Sarcopenia is characterized by a progressive age-related loss of muscle mass and strength. Aim: to evaluate the prevalence of sarcopenia and possible contributing factors associated with sarcopenia in RA patients. Patients and methods: Adult RA patients (n=105) of both gender and 100 subjects as control group (CG) matched by age, gender and BMI were included in this cross-sectional study. Whole-body composition was measured by DXA. Sarcopenia was defined according to EWGSOP2 as low muscle strength (handgrip) and low muscle mass (appendicular skeletal muscle mass -ASM- index by DXA). The association between sarcopenia and associated factors was evaluated using logistic regression analyses. Results: Significantly lower percentage of lean mass and ASM were found in the whole RA group compared to controls. However, lower lean parameters (total lea