Argentine Guidelines for Prevention and Treatment of Glucocorticoid-Induced Osteoporosis in Postmenopausal Women and Men aged 50 and older

BRANCE ML; LARROUDÉ MS; ZAMORA NV; BAGUR A; GRAF CE; GIACOIA E; DIEHL M; SOMMA LF; SCHNEEBERGER E; SALERNI HH; REY P; VARSAVSKY M; GONZÁLEZ DC; MASSARI F; SÁNCHEZ JA; GALICH AM; BERBOTTO G; GARCÍA ML; ZANCHETTA MB; MARTÍNEZ MUÑOZ A; CHAVERO I; RAMIREZ STIEBEN LA; MAHER MC; ABDALA R; PÉREZ B; DE LA VEGA MC; MANSUR JL; BRUN LR

JCR - JOURNAL OF CLINICAL RHEUMATOLOGY

LIPPINCOTT WILLIAMS & WILKINS

Lugar: Philadelphia; Año: 2023

1076-1608

bjective: To provide an evidence-based framework to guide health care professionals treating patients under GC therapy and develop guidelines for the prevention and treatment of glucocorticoid-induced osteoporosis (GIO) in postmenopausal women and men 50 years of age.Methods: An expert panel on bone diseases designed a series of clinically meaningful questions following the Population, Intervention, Comparator and Outcome (PICO) structure. Using Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology, we made a systematic literature review, extracted, and summarized the effect estimates, and graded the quality of the evidence. The expert panel voted each PICO question and made recommendations after reaching an agreement of at least 70%.Results: Seventeen recommendations (nine strong and eight conditional) and eight general principles were developed for postmenopausal women and men 50 years of age under GC treatment. Bone mineral density (B