Genetic requirements for infection-specific responses in conferring disease resistance in Arabidopsis

YOO, SUNG-JE; CHOI, HYO JU; NOH, SEONG WOO; CECCHINI, NICOLÁS M.; GREENBERG, JEAN T.; JUNG, HO WON

Frontiers in Plant Science

Frontiers

Año: 2022 vol. 13

mmunity in plants arises from defense regulatory circuits that can beconceptualized as modules. Both the types (and isolates) of pathogen andthe repertoire of plant receptors may cause different modules to be activatedand affect the magnitude of activation. Two major defense enzymes ofArabidopsis are ALD1 and ICS1/SID2. ALD1 is an aminotransferase needed forproducing the metabolites pipecolic acid, hydroxy-pipecolic acid, and possiblyother defense signals. ICS1/SID2 produces isochorismate, an intermediate inthe synthesis of salicylic acid (SA) and SA-derivatives. Metabolites resulting fromthe activation of these enzymes are found in petiole exudates and may serve aspriming signals for systemic disease resistance in Arabidopsis. Mutants lackingALD1 are known to have reduced SA accumulation. To further investigate therole of ALD1 in relation to the SA-related module, immunity phenotypes ofdouble mutants that disrupt ALD1 and ICS1/SID2 or SA perception by NPR1were compared with each sing