DUTTO, JEREMÍAS; BOFFELLI, LUCÍA; DHOOGE, SABRINA; ARAYA, PAULA; TOSELLO, JIMENA; FLORES GUIRADO, ANA PAULA; BUSTOS, JEREMIAS; BIASI, PILAR; VALERIANI, CARINA; PIAGGIO, ELIANE; ESPINOSA, JOAQUÍN; NUÑEZ, NICOLAS G.; MACCIONI, MARIANA

Immune dysregulation in children with Down Syndrome: Single-cell multi- omics reveal Th1-Skewed CD4 differentiation, reduced mature Tfh, and altered tonsillar architecture

Congreso SAI LXXIII - 4º Congreso Franco Argentino de Inmunología

Lugar: Rosario; Año: 2025;

BUSTOS, JEREMIAS; DUTTO JEREMIAS; TOSELLO, JIMENA; BIASI, PILAR; DHOOGE, SABRINA; FLORES GUIRADO, ANA PAULA; BOFFELLI, LUCÍA; NUÑEZ, NICOLÁS GONZALO; MACCIONI, MARIANA

Single Cell Proteomic and transcriptomic analysis of the tonsillar B cells from pediatric Down syndrome donors reveal enhanced antiviral transcriptomic programs

Congreso SAI LXXIII - 4º Congreso Franco Argentino de Inmunología

Lugar: Rosario; Año: 2025;

BIASI, PILAR; BOFFELLI, LUCÍA; BERNER, FIAMMA; FRIEBEL, EKATERINA; BUSTOS, JEREMIAS; DHOOGE, SABRINA; DUTTO, JEREMÍAS; FLORES GUIRADO, ANA PAULA; BECHER, BURKHARD; FLATZ, LUCAS; MACCIONI, MARIANA; NUÑEZ, NICOLÁS GONZALO

Distinct Cytokine Signatures of Toxicity In Anti-PD-1/CTLA-4 Therapy Not Observed With Anti-PD-1 Monotherapy

Congreso SAI LXXIII - 4º Congreso Franco Argentino de Inmunología

Lugar: Rosario; Año: 2025;

DHOOGE, SABRINA; FRIEBEL, EKATERINA; BOFFELLI, LUCÍA; DUTTO JEREMIAS; FLORES GUIRADO, ANA PAULA; BUSTOS, JEREMIAS; BIASI, PILAR; MOURON, SILVANA; QUINTELA-FANDINO, MIGUEL; BECHER, BURKHARD; MACCIONI, MARIANA; NUÑEZ, NICOLAS G.

Peripheral and Tumor Immune Signatures Predict Response to Immunotherapy in Advanced HER2-negative Breast Cancer

Congreso SAI LXXIII - 4º Congreso Franco Argentino de Inmunología

Lugar: Rosario; Año: 2025;

FLORES GUIRADO, ANA PAULA; DHOOGE, SABRINA; BOFFELLI, LUCÍA; DUTTO, JEREMÍAS; BUSTOS, JEREMIAS; BIASI, PILAR; ACOSTA RODRIGUEZ, EVA V.; MORÓN, GABRIEL; MALETTO, BELKYS A.; BECHER, BURKHARD; MACCIONI, MARIANA; NUÑEZ, NICOLÁS GONZALO

Homologous and heterologous COVID-19 vaccines imprint distinct innate immune signatures consistent with trained immunity

Congreso SAI LXXIII - 4º Congreso Franco Argentino de Inmunología

Lugar: Rosario; Año: 2025;

JEREMÍAS DUTTO; PAULA ARAYA; LUCÍA BOFFELLI; SABRINA DHOOGE; JIMENA TOSELLO; CARINA VALERIANI; ELIANE PIAGGIO; NICOLÁS NUÑEZ; JOAQUIN M. ESPINOSA; MARIANA MACCIONI

Understanding the immune dysregulation in children with trisomy 21: focus on the T-B cell cross-talk in secondary lymphoid organs

5th T21RS International Conference

Lugar: Roma; Año: 2024;

JEREMÍAS DUTTO; PAULA ARAYA; LUCÍA BOFFELLI; SABRINA DHOOGE; JIMENA TOSELLO; ANA PAULA FLORES; NICOLÁS NUÑEZ; ELIANE PIAGGIO; JOAQUIN M. ESPINOSA; MARIANA MACCIONI

Understanding the immune dysregulation in children with down syndrome: Are cxcr3+ T follicular helper cells involved in the autoimmune-prone profile reported in this population?

14th Latin American and Caribbean Congress of Immunology

Lugar: Buenos Aires; Año: 2024;

SABRINA DHOOGE; LUCÍA BOFFELLI; JEREMÍAS DUTTO; EKATERINA FRIEBEL; SILVANA MOURON; MARIANA MACCIONI; MIGUEL QUINTELA-FANDINO; BURKHARD BECHER; NICOLÁS NUÑEZ

Exploring immune biomarkers and survival associations in her2-negative breast cancer patients undergoing combination therapy with immune checkpoint inhibitors.

14th Latin American and Caribbean Congress of Immunology

Lugar: Buenos Aires; Año: 2024;

ANA PAULA FLORES; JONAS SCHMID; LAURA POWER; SABRINA DHOOGE; LUCÍA BOFFELLI; DUTTO JEREMIAS; LAURA CERVI; EVA ACOSTA RODRÍGUEZ; GABRIEL MORÓN; BELKYS MALETTO; BURKHARD BECHER; MARIANA MACCIONI; NICOLÁS NUÑEZ

Insights into differential reprogramming and trained immunity through comparative analysis of innate immune responses to diverse covid-19 vaccine regimens.

14th Latin American and Caribbean Congress of Immunology

Lugar: Buenos Aires; Año: 2024;

LUCÍA BOFFELLI; FIAMMA BERNER; EKATERINA FRIEBEL; SABRINA DHOOGE; DUTTO JEREMIAS; ANA PAULA FLORES; BURKHARD BECHER; LUKAS FLATZ; NICOLÁS NUÑEZ; MARIANA MACCIONI

Multi-approach analysis identifies tumor-derived 4EBP1 and CCL4 as potential serum biomarkers for immunotherapy response.

14th Latin American and Caribbean Congress of Immunology

Lugar: Buenos Aires; Año: 2024;

SOFIA LAGOS; ANA MAITE FOLLE; ANACLARA BEASLEY; MARTÍN FLÓ; FEDERICO CARRIÓN; OTTO PRISTCH; DUTTO JEREMIAS; MARIANA MACCIONI; JOSEP JULVE; ANA MARÍA FERREIRA

Two functions, one parasite lipoprotein: Antigen B uptakes cholesterol and acts as an efficient LPS-scavenger.

14th Latin American and Caribbean Congress of Immunology

Lugar: Buenos Aires; Año: 2024;

JEREMIAS DUTTO; PAULA ARAYA; LUCÍA BOFFELLI; SABRINA DHOOGE; JIMENA TOSELLO; ANA PAULA FLORES GUIRADO; ELIANE PIAGGIO; NICOLÁS NUÑEZ; JOAQUIN M. ESPINOSA; MARIANA MACCIONI

Exploring Dp16(1)/Yey mouse model to understand the enhanced susceptibility of children with trisomy 21 to respiratory tract infections: impact of a viral double-stranded RNA mimetic on lung immune cell populations.

14th Latin American and Caribbean Congress of Immunology

Lugar: Buenos Aires; Año: 2024;

JEREMÍAS DUTTO; PAULA ARAYA; LUCÍA BOFFELLI; SABRINA DHOOGE; NICOLÁS NUÑEZ; JOAQUIN M. ESPINOSA; MARIANA MACCIONI

Exploring Dp16(1)/Yey mouse model to understand the enhanced susceptibility of children with Trisomy 21 to respiratory tract Infections: impact of a viral double-stranded RNA mimetic on lung immune cell populations

5th T21RS International Conference

Lugar: Roma; Año: 2024;

JEREMÍAS DUTTO; PAULA ARAYA; LUCÍA BOFFELLI; SABRINA DHOOGE; JIMENA TOSELLO; CARINA VALERIANI; ELIANE PIAGGIO; NICOLÁS NUÑEZ; JOAQUIN M. ESPINOSA; MARIANA MACCIONI

Impact of trisomy 21 in tonsils: accumulation of T and B cells with phenotypes associated with inflammation and autoimmunity.

LXXI Reunión Científica Anual de la Sociedad Argentina de Inmunología SAI

Lugar: San Luis; Año: 2023;

SABRINA DHOOGE; EKATERINA FRIEBEL; SILVANA MOURON; JEREMÍAS DUTTO; LUCÍA BOFFELLI; MARIANA MACCIONI; MIGUEL QUINTELA-FANDINO; BURKHARD BECHER; NICOLÁS NUÑEZ

Exploration of immunophenotypic biomarkers and clinical responses in her2-negative breast cancer patients undergoing combination therapy of durvalumab and bevacizumab

LXXI Reunión Científica Anual de la Sociedad Argentina de Inmunología SAI

Lugar: San Luis; Año: 2023;

LUCÍA BOFFELLI; FIAMMA BERNER; EKATERINA FRIEBEL; SABRINA DHOOGE; JEREMÍAS DUTTO; BURKHARD BECHER; LUKAS FLATZ; NICOLÁS NÚNEZ; MARIANA MACCIONI

Exploring treatment response predictors in melanoma patients: high-throughput serum proteomics and immune cell analysis before and after checkpoint inhibitors therapy

LXXI Reunión Científica Anual de la Sociedad Argentina de Inmunología SAI

Lugar: San Luis; Año: 2023;

DUTTO, JEREMÍAS; BOFFELLI, LUCÍA; NUÑEZ, NICOLÁS GONZALO; MACCIONI, MARIANA

High dimensional analysis of tonsillar mononuclear cells reveals a profound bias toward inflammatory profiles

18th International Congress of Immunology - IUIS

Lugar: Cape Town; Año: 2023;

JEREMIAS DUTTO; PAULA ARAYA; LUCÍA BOFFELLI; JOAQUIN M. ESPINOSA; MARIANA MACCIONI

Dysregulation of the NK cell compartment in lungs of dp16(1)/yey mouse model of Down syndrome: impact of double-stranded RNA mimetic stimulation

REUNIÓN CONJUNTA SAIC SAI&FAIC SAFIS

Lugar: Mar del plata; Año: 2022;

LUCÍA BOFFELLI; CONSTANZA MARIN; JEREMÍAS DUTTO; FEDERICO RUIZ MORENO; BELKYS MALETTO; MARIANA MACCIONI

CPG-ODN formulated with coa-asc16 reduces the development of lung metastasis: conditioning of the pre-metastatic niche

REUNIÓN CONJUNTA SAIC SAI&FAIC SAFIS

Lugar: Mar del plata; Año: 2022;

SOFÍA LAGOS; ANA MAITE FOLLE; MARTÍN FLÓ; OTTO PRISTCH; JEREMÍAS DUTTO; MARIANA MACCIONI; ANA MARÍA FERREIRA

Echinococcus granulosus antigen B modulates lps-driven dendritic cell activation

REUNIÓN CONJUNTA SAIC SAI&FAIC SAFIS

Lugar: Mar del plata; Año: 2022;

JEREMIAS DUTTO; LUCÍA BOFFELLI; PAULA ARAYA; NICOLÁS NUÑEZ; JOAQUIN M. ESPINOSA; MARIANA MACCIONI

Altered follicular helper T cell (tfh) differentiation in tonsils of children with trisomy 21

REUNIÓN CONJUNTA SAIC SAI&FAIC SAFIS

Lugar: Mar del plata; Año: 2022;

JEREMIAS DUTTO; PAULA ARAYA; LUCÍA BOFFELLI; GERARDO GATTI; JOAQUIN M. ESPINOSA; MARIANA MACCIONI

Dysregulation of T cell lineages in tonsils of children with trisomy 21

4th International Conference of the Trisomy 21 Research Society

Lugar: Long Beach; Año: 2022;

JEREMIAS DUTTO; LUCÍA BOFFELLI; GERARDO GATTI; ADRIANA GRUPPI; MARIANA MACCIONI

The frequency of follicular helper T cells (Tfh) is diminished in tonsils from children with trisomy 21 whereas the fraction of pre-Tfh is increased and biased towards a Th1 profile

Reunión Anual de Sociedades de Biociencias SAIC-SAI-AAFE-NANOMED.AR

Lugar: Virtual; Año: 2021;

LUCÍA BOFFELLI; JEREMÍAS DUTTO; CONSTANZA MARIN; FEDERICO RUIZ MORENO; BELKYS MALETTO; MARIANA MACCIONI

CpG-ODN systemic administration before B16 melanoma cells inoculation increases tumor growth and decreases mice survival: analysis of the immune response elicited

Reunión Anual de Sociedades de Biociencias SAIC-SAI-AAFE-NANOMED.AR

Lugar: Virtual; Año: 2021;

LUISINA ONOFRIO; JEREMÍAS DUTTO; SABRINA BOSSIO; RUTH E. BAIGORRI; MARÍA BELÉN BRUGO; LAURA ALMADA; CONSTANZA MARÍN; FEDERICO RUIZ MORENO; XIMENA VOLPINI; MARIEL ALMEIDA; CAROLINA OLIVERA; NICOLÁS PONCE; JUAN NAHUEL QUIROZ; SILENE SILVERA RUIZ; LUCÍA BOFFELLI; EVA ACOSTA RODRÍGUEZ; CAROLINA AMEZCUA VESELY; DANIELA ARROYO; FABIO CERBÁN; LAURA CERVI; LAURA FOZZATTI; PAULA ICELY; PABLO IRIBARREN; BELKYS MALETTO; GABRIEL MORÓN; CECILIA RODRÍGUEZ GALÁN; CINTHIA STEMPIN; CLAUDIO ABIEGA; DAINA ESCUDERO; ADRIAN KAHN ; JUAN PABLO CAEIRO; MARIANA MACCIONI; CRISTINA MOTRÁN; LAURA CHIAPELLO; CAROLINA MONTES; ADRIANA GRUPPI; CLAUDIA E SOTOMAYOR

Phenotypic and functional characterization of peripheral T cell populations from COVID-19 patients hospitalized in Hospital Privado Universitario Córdoba- Argentina

Reunión Anual de Sociedades de Biociencias SAIC-SAI-AAFE-NANOMED.AR

Lugar: Virtual; Año: 2021;

JEREMIAS DUTTO; LAURA ALMADA; SOFIA C ANGIOLINI; NICOLÁS DHO; YAMILA GAZZONI; CLARISA MANZONE; CONSTANZA MARÍN; NICOLÁS E PONCE; PABLO IRIBARREN; FABIO CERBÁN; GABRIEL MORÓN; CAROLINA AMEZCUA VESELY; YAMILE ANA; LAURA CERVI; LAURA CHIAPELLO; LAURA FOZZATTI; PAULA ICELY; MARIANA MACCIONI; CRISTIAN MENA; CAROLINA MONTES; CRISTINA MOTRÁN; CECILIA RODRÍGUEZ GALÁN; CAROLINA MONTES; CRISTINA MOTRÁN; CECILIA RODRÍGUEZ GALÁN; CINTHIA STEMPIN; MARÍA ESTEFANIA VIANO; M BERTONE ; CLAUDIO ABIEGA; DAIANA ESCUDERO; ADRIAN KAHN; JUAN PABLO CAEIRO; DANIELA ARROYO; BELKYS MALETTO; EVA ACOSTA RODRÍGUEZ; ADRIANA GRUPPI; CLAUDIA E SOTOMAYOR

Dynamics of soluble immune mediators in covid-19 patients from an argentinean cohort with moderate and severe symptoms

Reunión Anual de Sociedades de Biociencias SAIC-SAI-AAFE-NANOMED.AR

Lugar: Virtual; Año: 2021;

BOFFELLI, LUCÍA; DUTTO, JEREMÍAS; GATTI, GERARDO; BETTS, COURTNEY; COUSSENS, LISA; MACCIONI, MARIANA

Setting up quantitative multiplex immunohistochemistry technology for the multiparametric analysis of the immune infiltrate of colorectal cancer tumors

Reunión Anual de Sociedades de Biociencias SAIC-SAI-SAFIS 2020

Lugar: Virtual; Año: 2020;

DUTTO, JEREMÍAS; BOFFELLI, LUCÍA; GATTI, GERARDO; MONTES, CECILIA; PACHECO, ÁLVARO; GARAY, AGUSTINA; KHAN, ADRIÁN ; MACCIONI, MARIANA

Analysis of the T and B cell compartments in tonsils of children with Trisomy 21

Reunión Anual de Sociedades de Biociencias SAIC-SAI-SAFIS 2020

Lugar: Virtual; Año: 2020;

BOFFELLI, LUCÍA; ROSELLI, EMILIANO; BARRIOS, BIBIANA; DUTTO, JEREMÍAS; PIQUERAS, VIRGINIA; MACCIONI, MARIANA; CORREA, SILVIA

Unsupervised computational analysis of flow cytometry for the immunophenotyping of lymphoid and myeloid subsets across tissues in c57bl6 and per2ko mice

LVII REUNIÓN ANUAL SAI 2019

Lugar: Tucumán; Año: 2019;

BOFFELLI, LUCÍA; ERRAMUSPE, CONSTANZA; DUTTO, JEREMÍAS; DEMARCHI, MARCELA; MACCIONI, MARIANA

Type-i ifn levels are associated with anti-dna antibodies in sle patients from cordoba, identifying a clinical subset that could benefit from anti- ifn drugs

LVII REUNIÓN ANUAL SAI 2019

Lugar: Tucumán; Año: 2019;

LUCÍA BOFFELLI; BIBIANA BARRIOS; EMILIANO ROSELLI; VIRGINIA PIQUERAS; JEREMÍAS DUTTO; MARIANA MACCIONI; SILVIA CORREA

Unsupervised computational analysis of flow cytometry for the immunophenotyping of lymphoid and myeloid subsets across tissues in c57bl6 and per2ko mice.

LVII REUNIÓN ANUAL SAI

Lugar: Tucumán; Año: 2019;

LUCÍA BOFFELLI; CONSTANZA ERRAMUSPE; JEREMÍAS DUTTO; MARCELA DEMARCHI; MARIANA MACCIONI

Type-i ifn levels are associated with anti-dna antibodies in sle patients from cordoba, identifying a clinical subset that could benefit from anti- ifn drugs.

LVII REUNIÓN ANUAL SAI

Lugar: Tucumán; Año: 2019;

JEREMÍAS DUTTO; ANAHÍ TURINA; EDUARDO CLOP; MARÍA ANGÉLICA PERILLO

Effect of natural terpenes on Bovine erythrocyte acetylcholinesterase (BEA) activity from bovine erythrocyte ghost membranes (BEM). Possible unspecific mechanism that tunes the BEA catalytic activity

XLVII Reunión Anual de la Sociedad Argentina de Biofísica

Lugar: La Plata; Año: 2018;