Carbon paste electrodes modified with electrogenerated magnetite and glucose oxidase. analytical applications for the highly selective and sensitive glucose biosensing

FAUSTO N. COMBA; MARÍA. D. RUBIANES; LOURDES CABRERA,; SILVIA GUTIÉRREZ; PILAR HERRASTI; GUSTAVO A. RIVAS

Wiley-VCH Verlang GmbH & Co, KgaA, Weinheimv

Lugar: Las Cruces, New México, EEUU; Año: 2010 vol. 22 p. 1566 - 1566

his work reports the advantages of carbon paste electrodes modified with electrogenerated magnetite nanoparticles. The nanoparticles present catalytic activity towards reduction hydrogen peroxide reduction. The incorporation of glucose oxidase (GOx) with magnetite in a carbon paste matrix have made possible the development of an efficient glucose biosensor. The effect of the amount of GOx and magnetite present in the composite on the response of the biosensor was critically evaluated. The biosensors demonstrated to be highly selective, with negligible interference of ascorbic acid and uric acid. The proposed biosensor was challenged with human blood serum demonstrating an excellent correlation with the spectrophotometric method.