Dopamine and Glucose Sensors Based on Glassy Carbon Modified With Melanic Polymers.

ROSA GONZÁLEZ; ALBERTO SANCHEZ; MANUEL CHICHARRO; MARÍA D. RUBIANES; GUSTAVO A. RIVAS

Wiley-VCH Verlang GmbH & Co, KgaA, Weinheim

Lugar: Las Cruces, New México State, EEUU; Año: 2004 vol. 16 p. 1244 - 1244

p class="MsoNormal" style="margin: 0cm 0cm 0pt 36pt; text-align: justify;">This work deals with the study of polymers electrogenerated from different catechols at glassy carbon electrodes and the analytical applications of the resulting modified electrodes for dopamine quantification and glucose biosensing. The electropolymerization was performed from a 3.0 x 10-3 M catechol solution (catechol, dopamine, norepinephrine, epinephrine or L-dopa in a 0.050 M phosphate buffer pH 7.40) by applying 1.00 V for 60 min. The properties of the polymers are very dependent on the nature of the catechol, L-dopa being the best. Glassy carbon electrodes modified with melanic polymers electrogenerated from L-dopa and norepinephrine were found to be suitable for dopamine determinations in flow systems, although the behavior was highly dependent on the nature of the monomer. Detection limits of 5.0nM dopamine and interferences of 9.0