Use of a Melanin-Type Polymer to Improve the Selectivity of Glucose Biosensors.

M. D. RUBIANES AND G. A. RIVAS

ANALYTICAL LETTERS

Marcel Dekker

Lugar: Cork, Ireland; Año: 2003 vol. 36 p. 1311 - 1311

0003-2719

his paper reports the advantages of using a melanin-type polymer to improve the selectivity of glucose biosensors based on carbon paste electrodes containing Pt and glucose oxidase (Gox). The resulting bioelectrodes combine the high sensitivity of metallized electrodes with the the selectivity given by the polymeric layer. They exhibit excellent performance for glucose with a rapid response (around 10 sec per sample), a wide linear range (up to 3.0 x 10-2 M), low detection limits and a highly reproducible response (R.S.D. of 4.9 %). The bioelectrodes are stable with prolonged use and almost free from the interference of easily oxidizable compounds found in biological fluids, such as ascorbic acid (AA), uric acid (UA) and acetaminophen.