Carbon nanomaterials-based electrochemical cancer biomarkers biosensors

MARCELA C. RODRÍGUEZ, MARÍA D. RUBIANES, PABLO GALLAY, MICHAEL LÓPEZ MUJICA, ANTONELLA MONTEMERLO, FABRIZIO PERRACHIONE, DAIANA F. REARTES AND GUSTAVO A. RIVAS; SOLEDAD BOLLO DRAGNIC; PABLO DALMASSO, LUIS A. TAMBORELLI, VIRGINIA VASCHETTI; SIBEL OZKAN

The detection of biomarkers:past, present and the future prospects

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Lugar: Cambridge, Massachusetts; Año: 2021; p. 225 - 247

This chapter presents a critical discussion about the most relevant carbon nanomaterials-based electrochemical biosensors for the quantification of typical cancer biomarkers like microRNAs, prostate-specific antigen, alpha-fetoprotein, and carcinoembryonic antigen reported in the period 2015-2020. The analysis is focused on the strategies used to build the biosensing platforms, from the selection and immobilization of the biorecognition element, to the transduction of the bioaffinity event into a measurable signal, with special emphasis on the analytical characteristics of the resulting biosensors.