A novel lipid binding protein is a factor required for MgATP stimulation of the squid nerve Na+/Ca2+ exchanger.

BERBERIAN G, BOLLO M, MONTICH GG, ROBERTS G, DEGIORGIS JA, DIPOLO R, AND BEAUGE L.

Elsevier

Año: 2009 vol. 1788 p. 1255 - 1255

font color="#231f20" size="1" face="AdvTT5235d5a9"> Here we identify a cytosolic factor essential for MgATP up-regulation of the squid nerve Na+/Ca2+ exchanger. Mass spectroscopy and Western blot analysis established that this factor is a member of the lipocalin super family of lipid binding proteins of 132 amino acids in length. We named it Regulatory protein of the squid nerve sodium calcium exchanger (ReP1-NCXSQ). ReP-1-NCXSQ was cloned, over expressed and purifi