Immunodominant proteins á-1 giardin and â-giardin are expressed in both assemblages A and B of Giardia lamblia

FELIZIANI C; MERINO MC; RIVERO MR; HELLMAN U; PISTORESI MARIA CRISTINA; ANDREA SILVANA ROPOLO

BIOMED CENTRAL LTD

Año: 2011 vol. 11 p. 233 - 233

p class="MsoNormal" style="margin: 0cm 0cm 0pt; line-height: 200%; text-indent: 0cm;">Background: To date, eight assemblages of Giardia lamblia have been described, but only assemblages A and B are known to infect humans. Despite the fact that the genomic, biological, and clinical differences found between these two assemblages has raised the possibility that they may be considered different species, there is relatively limited information on their phenotypic differences. In the present study, we developed monoclonal antibodies against alpha-1 and beta giardin, two immunodominant proteins produced during