Identification of Variant-specific surface proteins in Giardia muris trophozoites

ANDREA SILVANA ROPOLO; SAURA A; CARRANZA P; LUJAN HD

AMER SOC MICROBIOLOGY

Año: 2005 vol. 73 p. 5208 - 5208

b> Giardia lamblia undergoes antigenic variation, a process that might allow the parasite to evade the host’s immune response and adapt to different environments. Here we show that Giardia muris, a related species that naturally infects rodents, possesses multiple variant-specific surface proteins (VSPs) and expresses VSPs on its surface, suggesting that it undergoes antigenic variation similar to that of G. lamblia