Adaptor Protein 2 Regulates Receptor-Mediated Endocytosis and Cyst Formation in Giardia lamblia

RIVERO MR; VRANYCH CV; BISBAL MARIANO; MALETTO, BELKYS ANGELICA; ROPOLO, ANDREA SILVANA; TOUZ MC

PORTLAND PRESS LTD

Año: 2010 vol. 428 p. 33 - 33

font size="3" face="TimesNewRomanPSMT"> The parasite Giardia lamblia possesses peripheral vacuoles (PVs) that function as both endosomes and lysosomes and are implicated in the adaptation, differentiation, and survival of the parasite in different environments. The mechanisms by which Giardia traffics essential proteins to these organelles and regulates their secretion have important implications in the control of parasite dissemination. In this study, we describe the participation of the heterotetrameric clathrin-adaptor protein gA