SUMOylation in Giardia lamblia: A Conserved Pos-translational Modification in one of the earliest divergent eukaryotes

VRANYCH CV; MERINO MC; ZAMPONI N; TOUZ MC; ANDREA SILVANA ROPOLO

Biomolecules

MDPI

Año: 2012 vol. 2 p. 312 - 312

2218-273X

font face="TimesNewRomanPSMT"> Post-translational modifications are able to regulate protein function and cellular processes in a rapid and reversible way. SUMOylation, the post-translational modification of proteins by the addition of SUMO, is a highly conserved process that seems to be present in modern cells. However, the mechanism of protein SUMOylation in earlier divergent eukaryotes, such as Giardia lamblia, is only starting to become apparent. In this work, we report the presence of a single SUMO gene encoding to SUMO protein in Giardia.